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- Vail, Vaill, Ails, Vails
- Vala, From Vala in Portugal
- Valdez, Waldo, Valdo, Son of Valdo
- Valencia, Valor, Courage
- Valentine, Volentine, Nollintine
- Valenzuela, Valencia, Little Valencia in Spain
- Van Alen, Van Allen, Van Allan
- VanBuren, Buren, Buran, Beuren, Van Buran
- Van Buskirk, Boskerick, Van Buskirkt
- VanCleve, Cleaf, Cleave, Cleft, VanClief
- Vanderbilt, Vanderbuilt, Van Derbilt
- Van Der Poel, Van Der Pool, Vanderpool
- Vanderslice, VanDerSluiss, VanDerSloss
- Van Der Veer, Vandiver, Vandyver, Vandivier
- Van Deusen, Dusen, Duzen, Van
- Van Doren, Doorn, Dorn, Van
- Van Dyke, Dyke, Dyck, Van Dyck
- Van Evera, Van Every, Van Vere
- Vang, Meadow, Field
- Van Gordon, Van Gorden, Van Gordan, VanGorder
- VanHook, VanHooke, VanHooks
- VanHorn, Vanhorn, VanHorne, Horne
- Van Leer, VanLaer, Vanlear, Van Lohr, Leer
- VanLew, Vanloo, Vanlou, VanLue
- VanLoon, VanLoone, Vanloon
- Vanmetter, VanMeter, VanMetter, VanMetre
- VanNess, Nest, Neste, Van,
- VanRiper, VanRipen, VanRippen
- VanSchick, Schaack, Schoick, Scyoc, Skayhalk, Skiehawk
- VanSickle, Sickelen, Sickle, Van Sicklin, VanSlyke, VanSlick, Slyck, Slyoke
- VanVoorhees, VanVoorhees, Voorhees, Voorhies, Vorhis, Vories, Voris, Vorys
- VanVleet, Fleet, Flit, Vilet
- VanVorst, VanBorst, VanHorst
- VanVranken, VanVrken, Van Vrancken
- VanWagenen, VanWagonen, VanWagenin
- VanWert, Vanwert, Vanwerte
- VanWinkle, VanWinkel, Vanwinkle
- VanWormer, Vanwormer, Wormer, Van Wormor
- VanZant, VanZandt, VanSant
- Vara, Thin Stick, Thin People
- Vargas, Pasture, From the Pasture
- Vasquez, Vasco, Son of Vasco, Vazquez, Son of Velasco
- Vaughan, Vaughn, Van, Vann, Von
- Vaught, Vought, Vaght
- Vawter, Vater, Vauter
- Veale, Veal, Veile
- Veasey, Vesey, Vessy, Veazey, Veazy, Veazie, Veaze
- Veech, Veach, Veatch, Veitch
- Vega, Meadow, Plain Meadow, From a Plain Meadow
- Vela, From Vela in Portugal
- Velarde, Valarde, Velard
- Velasquez, Velasco, Son of Velasco, Velazquez
- Velez, Vigilant, Vigilant People
- Venicomb, Venicombe, Venicomp
- Vermillion, Vermilion, Vermillian
- Verona, Werona, Verrona
- Versailles, Versailes
- Ver Valen, Van Valin, Ver Valin
- Vest, Veste, Veast
- Vestal, Vestle, Vestel
- Vicker, Victer, Vicktor, Vicars, Vickars
- Viele, Vears, Vellie, Velie
- Vienna, Viena
- Villalobos, Village of Wolves
- Villanueva, New Town
- Villarreal, Royal Estate or Village
- Villavencencio, Villavinscencio, Villavinsio
- Villa, Homestead, Village
- Villegas, Home near the Village
- Vining, Vinin, Vinen
- Vinson, Vintson, Vincent, Vinton
- Vint, Vent, Vient
- Virden, Varden, Virten
- Vo, Fighter, Soldier
- Vose, Vosse, Vos, Voce
- Voshell, Voshall, Voshal
- Vought, Vaught, Voigt, Vogt, Vote
- Vreeland, Freeland, Vreelandt
- Vu, Fighter, Soldier
