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- Eager, Eagger, Egger, Ebern
- Earhart, Earheart, Everhart, Ehrehart, Everharth
- Earl, Earls, Erol, Earle, Earles, Earls
- Easterday, Ostertag, Yesterday
- Eastlake, Eastlke, Eastlak
- Eastland, Eastlan, Eastin
- Eastman, Easton, Easten, Eastham, Eastam
- Easton, Eastin, Eastan, Easten, Eyestone
- Eastwood, Eastward, Eastwordis,
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- Ebaugh, Ebough, Epaugh
- Eberhardt, Eberhard, Eberhart
- Eblin, Ebeling, Ebling
- Ebner, Ebene, Flat, Plateau, Judge
- Ebrahimi, Ebrahim, Ebrohim
- Ebrsol, Ebrsoll, Ebersol
- Eccleston, Ecclestone, Ecclesia, Church Town
- Echevarria, Echeverria, Etxeberria
- Eck, Ech, Ecke, Eche
- Eckert, Acker, Akart, Eckard, Eckart, Echart
- Eckles, Eckle, Eckel, Eckels, Eskle, Echols, Erckle
- Eckstein, Edgestone, Eccstein
- Eddington, Edington, Eddinton, Eddingston
- Eddy, Eddie, Edie
- Edelen, Eddelyn, Edelyne
- Edelman, Eddlemen, Edleman Edelmen
- Edgar, Edger, Eddger
- Edgerton, Edgarton, Egerton
- Edmondson, Edmiston, Edmonson, Edmonston, Edmundson
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- Egawa, Ekawa, Bay, Inlet
- Egger, Eggar, Eggen, Farmer
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- Eglitis, Egle. Spruce Tree
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- Eicholtz, Eicholts, Eigholtzs
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- El Hashem, Al Hashim, El Hashem
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- Elwes, Elvis, Eloise
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- Escobar, Overgrown with Green Stems
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- Escarra, Esquerra, Lefthanded
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- Esparza, Swordsman, Soldier
- Espensen, Son of Espen, Espenson
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- Espindola, Facundus, Fluent People
- Espinoza, Thorny, From a Thorny Area, Espinosa
- Esplin, Esplen, Esplind
- Esposito, Espositoe, Exposito, Exposed
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- Esquivel, Behind the Lime Tree
- Esser, Essert, Axle
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- Estrada, Street, Way
- Eszes, Clever, Bright
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- Etxebarria, Echeverria, Echeveria
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- Eudy, Oudy, Udy, Uty, Dauty, Douty, Yuder
- Euclid, Euclide, Euclids
- Eustis, Eutace, Eutise
- Evangelista, Evangelist, Evangelists
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- Evelyn, Aveline, Evelin, Evelan
- Evered, Everard, Evererd, Everett
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- Everill. Everell, Everele, Eoforhild
- Everly, Everley, Everlie
- Evers, Everst, Evert
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- Every, Everie, Everry
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- Ewing, Ewinge, Ewin, Euan
- Eygenaar, Eganar, Egenar, Egenor, Eggenaar, Egner, Eigenaar, Eigennar, Eigener, Eighenar, Eigner, Eygenaer, Eygner
- Eyler, Eiler, Eilert, Eylar, Iler, Oiler, Oilwe, Oyler
- Ezekiel, Ezekeil, Ezekiell
- Ezell, Ezel, Ezelle, Esell, Essell, Essell, Issel, Isell, Izell, Izzel, Izel, Uzell, Uzelle, Uzell
